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Alzheimer’s disease mouse model when administered at an advanced stage of disease progression. J Alzheimers Dis. 2011;26(1):187–97. https://pubmed.ncbi.nlm.nih.gov/21593570/

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Bourassa MW, Alim I, Bultman SJ, Ratan RR. Butyrate, neuroepigenetics and the gut microbiome: can a high fiber diet improve brain health? Neurosci Lett. 2016;625:56–63. https://pubmed.ncbi.nlm.nih.gov/26868600/

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Chen T, Kim CY, Kaur A, et al. Dietary fibre-based SCFA mixtures promote both protection and repair of intestinal epithelial barrier function in a Caco-2 cell model. Food Funct. 2017;8(3):1166–73. https://pubmed.ncbi.nlm.nih.gov/28174773/

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Braniste V, Al-Asmakh M, Kowal C, et al. The gut microbiota influences blood-brain barrier permeability in mice. Sci Transl Med. 2014;6(263):263ra158. https://pubmed.ncbi.nlm.nih.gov/25411471/

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Bercik P, Park AJ, Sinclair D, et al. The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication. Neurogastroenterol Motil. 2011;23(12):1132–9. https://pubmed.ncbi.nlm.nih.gov/21988661/

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Bravo JA, Forsythe P, Chew MV, et al. Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proc Natl Acad Sci U S A. 2011;108(38):16050–5. https://pubmed.ncbi.nlm.nih.gov/21876150/

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Clark KB, Naritoku DK, Smith DC, Browning RA, Jensen RA. Enhanced recognition memory following vagus nerve stimulation in human subjects. Nat Neurosci. 1999;2(1):94–8. https://pubmed.ncbi.nlm.nih.gov/10195186/

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Liyanage SI, Vilekar P, Weaver DF. Nutrients in Alzheimer’s disease: the interaction of diet, drugs and disease. Can J Neurol Sci. 2019;46(1):23–34. https://pubmed.ncbi.nlm.nih.gov/30688198/

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McGrattan AM, McGuinness B, McKinley MC, et al. Diet and inflammation in cognitive ageing and Alzheimer’s disease. Curr Nutr Rep. 2019;8(2):53–65. https://pubmed.ncbi.nlm.nih.gov/30949921/

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David LA, Maurice CF, Carmody RN, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014;505(7484):559–63. https://pubmed.ncbi.nlm.nih.gov/24336217/

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van Soest APM, Hermes GDA, Berendsen AAM, et al. Associations between pro– and anti-inflammatory gastro-intestinal microbiota, diet, and cognitive functioning in Dutch healthy older adults: the NU-AGE Study. Nutrients. 2020;12(11):E3471. https://pubmed.ncbi.nlm.nih.gov/33198235/

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Bruce-Keller AJ, Salbaum JM, Luo M, et al. Obese-type gut microbiota induce neurobehavioral changes in the absence of obesity. Biol Psychiatry. 2015;77(7):607–15. https://pubmed.ncbi.nlm.nih.gov/25173628/

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Loeb MB, Molloy DW, Smieja M, et al. A randomized, controlled trial of doxycycline and rifampin for patients with Alzheimer’s disease. J Am Geriatr Soc. 2004;52(3):381–7. https://pubmed.ncbi.nlm.nih.gov/14962152/

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Molloy DW, Standish TI, Zhou Q, Guyatt G, The DARAD Study Group. A multicenter, blinded, randomized, factorial controlled trial of doxycycline and rifampin for treatment of Alzheimer’s disease: the DARAD trial. Int J Geriatr Psychiatry. 2013;28(5):463–70. https://pubmed.ncbi.nlm.nih.gov/22718435/

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Marx W, Scholey A, Firth J, et al. Prebiotics, probiotics, fermented foods and cognitive outcomes: a meta-analysis of randomized controlled trials. Neurosci Biobehav Rev. 2020;118:472–84. https://pubmed.ncbi.nlm.nih.gov/32860802/

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Benton D, Williams C, Brown A. Impact of consuming a milk drink containing a probiotic on mood and cognition. Eur J Clin Nutr. 2007;61(3):355–61. https://pubmed.ncbi.nlm.nih.gov/17151594/

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Den H, Dong X, Chen M, Zou Z. Efficacy of probiotics on cognition, and biomarkers of inflammation and oxidative stress in adults with Alzheimer’s disease or mild cognitive impairment – a meta-analysis of randomized controlled trials. Aging (Albany NY). 2020;12(4):4010–39. https://pubmed.ncbi.nlm.nih.gov/32062613/

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Ito K, Romero K. Placebo effect in subjects with cognitive impairment. Int Rev Neurobiol. 2020;153:213–30. https://pubmed.ncbi.nlm.nih.gov/32563289/

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Block BR, Albanese SG, Hume AL. Online promotion of “brain health” supplements. Sr Care Pharm. 2021;36(10):489–92. https://pubmed.ncbi.nlm.nih.gov/34593090/

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Stoehr GP, Jacobsen E, Jia Y, Snitz BE, Ganguli M. Trends in the use of medications and supplements to treat or prevent dementia: a population-based study. Alzheimer Dis Assoc Disord. 2020;34(2):148–55. https://pubmed.ncbi.nlm.nih.gov/31633558/

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Block BR, Albanese SG, Hume AL. Online promotion of “brain health” supplements. Sr Care Pharm. 2021;36(10):489–92. https://pubmed.ncbi.nlm.nih.gov/34593090/

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Case 1:17-cv-00124-LLS Document 72. Federal Trade Commission and People of the State of New York v Quincy Bioscience Holding Company, Inc. https://www.ftc.gov/system/files/documents/cases/quincy_bioscience_opinion_and_order.pdf. Published July 14, 2019. Accessed July 10, 2022.; https://www.ftc.gov/system/files/documents/cases/quincy_bioscience_opinion_and_order.pdf

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Fair L. Prevagen complaint suggests mindfulness about memory claims. Federal Trade Commission. https://www.ftc.gov/business-guidance/blog/2017/01/prevagen-complaint-suggests-mindfulness-about-memory-claims. Published January 9, 2017. Accessed June 21, 2022.; https://www.ftc.gov/business-guidance/blog/2017/01/prevagen-complaint-suggests-mindfulness-about-memory-claims

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Gabriel BA. AARP asks court to declare Prevagen ads misleading. AARP. https://www.aarp.org/politics-society/advocacy/info-2018/overturn-prevagen-decision-fd.html. Published March 21, 2018. Accessed June 21, 2022.; https://www.aarp.org/politics-society/advocacy/info-2018/overturn-prevagen-decision-fd.html

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Scott GN. Does Prevagen® help memory loss? Medscape. https://www.medscape.com/viewarticle/860395. Published March 18, 2016. Accessed June 21, 2022.; https://www.medscape.com/viewarticle/860395

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Eisner C. Americans took Prevagen for years – as the FDA questioned its safety. Wired. https://www.wired.com/story/prevagen-made-millions-fda-questioned-safety/. Published October 21, 2020. Accessed June 21, 2022.; https://www.wired.com/story/prevagen-made-millions-fda-questioned-safety/

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Crawford C, Deuster PA. Be in the know: dietary supplements for cognitive performance. J Spec Oper Med. 2020;20(2):132–5. https://pubmed.ncbi.nlm.nih.gov/32573750/

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Crawford C, Boyd C, Avula B, Wang YH, Khan IA, Deuster PA. A public health issue: dietary supplements promoted for brain health and cognitive performance. J Altern Complement Med. 2020;26(4):265–72. https://pubmed.ncbi.nlm.nih.gov/32119795/

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Block BR, Albanese SG, Hume AL. Online promotion of “brain health” supplements. Sr Care Pharm. 2021;36(10):489–92. https://pubmed.ncbi.nlm.nih.gov/34593090/

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Franke AG, Heinrich I, Lieb K, Fellgiebel A. The use of Ginkgo biloba in healthy elderly. Age (Dordr). 2014;36(1):435–44. https://pubmed.ncbi.nlm.nih.gov/23736956/

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Yuan Q, Wang CW, Shi J, Lin ZX. Effects of Ginkgo biloba on dementia: an overview of systematic reviews. J

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