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Wang M, Monticone RE, McGraw KR. Proinflammation, profibrosis, and arterial aging. Aging Med (Milton). 2020;3(3):159–68. https://pubmed.ncbi.nlm.nih.gov/33103036/
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Weech M, Altowaijri H, Mayneris-Perxachs J, et al. Replacement of dietary saturated fat with unsaturated fats increases numbers of circulating endothelial progenitor cells and decreases numbers of microparticles: findings from the randomized, controlled Dietary Intervention and VAScular function (DIVAS) study. Am J Clin Nutr. 2018;107(6):876–82. https://pubmed.ncbi.nlm.nih.gov/29741564/
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Shi Q, Hubbard GB, Kushwaha RS, et al. Endothelial senescence after high-cholesterol, high-fat diet challenge in baboons. Am J Physiol Heart Circ Physiol. 2007;292(6):H2913–20. https://pubmed.ncbi.nlm.nih.gov/17277030/
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Jeong HS, Kim S, Hong SJ, et al. Black raspberry extract increased circulating endothelial progenitor cells and improved arterial stiffness in patients with metabolic syndrome: a randomized controlled trial. J Med Food. 2016;19(4):346–52. https://pubmed.ncbi.nlm.nih.gov/26891216/
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Choi EY, Lee H, Woo JS, et al. Effect of onion peel extract on endothelial function and endothelial progenitor cells in overweight and obese individuals. Nutrition. 2015;31(9):1131–5. https://pubmed.ncbi.nlm.nih.gov/26233871/
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Kim W, Jeong MH, Cho SH, et al. Effect of green tea consumption on endothelial function and circulating endothelial progenitor cells in chronic smokers. Circ J. 2006;70(8):1052–7. https://pubmed.ncbi.nlm.nih.gov/16864941/
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Keith M, Kuliszewski MA, Liao C, et al. A modified portfolio diet complements medical management to reduce cardiovascular risk factors in diabetic patients with coronary artery disease. Clin Nutr. 2015;34(3):541–8. https://pubmed.ncbi.nlm.nih.gov/25023926/
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Steinberg D, Blumenthal S, Carleton RA, et al. Lowering blood cholesterol to prevent heart disease: NIH Consensus Development Conference statement. Nutr Rev. 1985;43(9):283–91. https://pubmed.ncbi.nlm.nih.gov/4058807/
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Ference BA, Ginsberg HN, Graham I, et al. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel. Eur Heart J. 2017;38(32):2459–72. https://pubmed.ncbi.nlm.nih.gov/28444290/
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Roberts WC. It’s the cholesterol, stupid! Am J Cardiol. 2010;106(9):1364–6. https://pubmed.ncbi.nlm.nih.gov/21029840/
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Roberts WC. William Clifford Roberts, MD curriculum vitae. http://www.iscvdp.org/docs/WCRoberts-CV.pdf. Accessed May 13, 2022.;http://www.iscvdp.org/storage/app/media/william-clifford-roberts.pdf
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Roberts WC. Quantitative extent of atherosclerotic plaque in the major epicardial coronary arteries in patients with fatal coronary heart disease, in coronary endarterectomy specimens, in aorta – coronary saphenous venous conduits, and means to prevent the plaques: a review after studying the coronary arteries for 50 years. Am J Cardiol. 2018;121(11):1413–35. https://pubmed.ncbi.nlm.nih.gov/29753395/
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Ference BA, Ginsberg HN, Graham I, et al. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel. Eur Heart J. 2017;38(32):2459–72. https://pubmed.ncbi.nlm.nih.gov/28444290/
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Fernández-Friera L, Fuster V, López-Melgar B, et al. Normal LDL – cholesterol levels are associated with subclinical atherosclerosis in the absence of risk factors. J Am Coll Cardiol. 2017;70(24):2979–91. https://pubmed.ncbi.nlm.nih.gov/29241485/
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Nambi V, Bhatt DL. Primary prevention of atherosclerosis: time to take a selfie? J Am Coll Cardiol. 2017;70(24):2992–4. https://pubmed.ncbi.nlm.nih.gov/29241486/
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Hochholzer W, Giugliano RP. Lipid lowering goals: back to nature? Ther Adv Cardiovasc Dis. 2010;4(3):185–91. https://pubmed.ncbi.nlm.nih.gov/20400493/
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Fernández-Friera L, Fuster V, López-Melgar B, et al. Normal LDL – cholesterol levels are associated with subclinical atherosclerosis in the absence of risk factors. J Am Coll Cardiol. 2017;70(24):2979–91. https://pubmed.ncbi.nlm.nih.gov/29241485/
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Gitin A, Pfeffer MA, Hennekens CH. Editorial commentary: the lower the LDL the better but how and how much? Trends Cardiovasc Med. 2018;28(5):355–6. https://pubmed.ncbi.nlm.nih.gov/29428160/
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Law MR, Wald NJ. Risk factor thresholds: their existence under scrutiny. BMJ. 2002;324(7353):1570–6. https://pubmed.ncbi.nlm.nih.gov/12089098/
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Hochholzer W, Giugliano RP. Lipid lowering goals: back to nature? Ther Adv Cardiovasc Dis. 2010;4(3):185–91. https://pubmed.ncbi.nlm.nih.gov/20400493/
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O’Keefe JH, Cordain L, Harris WH, Moe RM, Vogel R. Optimal low-density lipoprotein is 50 to 70 mg/dL: lower is better and physiologically normal. J Am Coll Cardiol. 2004;43(11):2142–6. https://pubmed.ncbi.nlm.nih.gov/15172426/
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Anderson JW, Konz EC, Jenkins DJ. Health advantages and disadvantages of weight-reducing diets: a computer analysis and critical review. J Am Coll Nutr. 2000;19(5):578–90. https://pubmed.ncbi.nlm.nih.gov/11022871/
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Hochholzer W, Giugliano RP. Lipid lowering goals: back to nature? Ther Adv Cardiovasc Dis. 2010;4(3):185–91. https://pubmed.ncbi.nlm.nih.gov/20400493/
3599
Law MR, Wald NJ. Risk factor thresholds: their existence under scrutiny. BMJ. 2002;324(7353):1570–6. https://pubmed.ncbi.nlm.nih.gov/12089098/
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Roberts WC. Quantitative extent of atherosclerotic plaque in the major epicardial coronary arteries in patients with fatal coronary heart disease, in coronary endarterectomy specimens, in aorta – coronary saphenous venous conduits, and means to prevent the plaques: a review after studying the coronary arteries for 50 years. Am J Cardiol. 2018;121(11):1413–35. https://pubmed.ncbi.nlm.nih.gov/29753395/
3601
Packard CJ. LDL cholesterol: How low to go? Trends Cardiovasc Med. 2018;28(5):348–54. https://pubmed.ncbi.nlm.nih.gov/29336946/
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Packard CJ. LDL cholesterol: How low to go? Trends Cardiovasc Med. 2018;28(5):348–54. https://pubmed.ncbi.nlm.nih.gov/29336946/
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Nambi V, Bhatt DL. Primary prevention of atherosclerosis: time to take a selfie? J Am Coll Cardiol. 2017;70(24):2992–4. https://pubmed.ncbi.nlm.nih.gov/29241486/
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Hong KN, Fuster V, Rosenson RS, Rosendorff C, Bhatt DL. How low to go with glucose, cholesterol, and blood pressure in primary prevention of CVD. J Am Coll Cardiol. 2017;70(17):2171–85. https://pubmed.ncbi.nlm.nih.gov/29050566/
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Baigent C, Blackwell L, Emberson J, et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data