Health. 2017;23(2):71–5. https://pubmed.ncbi.nlm.nih.gov/28643614/

4193

Prentice RL, Howard BV, Van Horn L, et al. Nutritional epidemiology and the Women’s Health Initiative: a review. Am J Clin Nutr. 2021;113(5):1083–92. https://pubmed.ncbi.nlm.nih.gov/33876183/

4194

Patterson RE, Kristal A, Rodabough R, et al. Changes in food sources of dietary fat in response to an intensive low-fat dietary intervention: early results from the Women’s Health Initiative. J Am Diet Assoc. 2003;103(4):454–60. https://pubmed.ncbi.nlm.nih.gov/12669007/

4195

Patterson RE, Prentice RL, Beresford S, et al. Dietary adherence in the Women’s Health Initiative dietary modification trial. J Am Diet Assoc. 2004;104(4):654–8. https://pubmed.ncbi.nlm.nih.gov/15054353/

4196

Kroenke CH, Caan BJ, Stefanick ML, et al. Effects of a dietary intervention and weight change on vasomotor symptoms in the Women’s Health Initiative. Menopause. 2012;19(9):980–8. https://pubmed.ncbi.nlm.nih.gov/22781782/

4197

Rotolo O, Zinzi I, Veronese N, et al. Women in LOVe: lacto-ovo-vegetarian diet rich in omega-3 improves vasomotor symptoms in postmenopausal women. An exploratory randomized controlled trial. Endocr Metab Immune Disord Drug Targets. 2019;19(8):1232–9. https://pubmed.ncbi.nlm.nih.gov/31132980/

4198

Cetisli NE, Saruhan A, Kivcak B. The effects of flaxseed on menopausal symptoms and quality of life. Holist Nurs Pract. 2015;29(3):151–7. https://pubmed.ncbi.nlm.nih.gov/25882265/

4199

Messina M. Soy and health update: evaluation of the clinical and epidemiologic literature. Nutrients. 2016;8(12):E754. https://pubmed.ncbi.nlm.nih.gov/27886135/

4200

Thomas AJ, Ismail R, Taylor-Swanson L, et al. Effects of isoflavones and amino acid therapies for hot flashes and co-occurring symptoms during the menopausal transition and early postmenopause: a systematic review. Maturitas. 2014;78(4):263–76. https://pubmed.ncbi.nlm.nih.gov/24951101/

4201

Avis NE, Crawford SL, Greendale G, et al. Duration of menopausal vasomotor symptoms over the menopause transition. JAMA Intern Med. 2015;175(4):531–9. https://pubmed.ncbi.nlm.nih.gov/25686030/

4202

Avis NE, Kaufert PA, Lock M, McKinlay SM, Vass K. The evolution of menopausal symptoms. Baillieres Clin Endocrinol Metab. 1993;7(1):17–32. https://pubmed.ncbi.nlm.nih.gov/8435051/

4203

Thomas AJ, Ismail R, Taylor-Swanson L, et al. Effects of isoflavones and amino acid therapies for hot flashes and co-occurring symptoms during the menopausal transition and early postmenopause: a systematic review. Maturitas. 2014;78(4):263–76. https://pubmed.ncbi.nlm.nih.gov/24951101/

4204

Lock M. Contested meanings of the menopause. Lancet. 1991;337(8752):1270–2. https://pubmed.ncbi.nlm.nih.gov/1674073/

4205

Avis NE, Kaufert PA, Lock M, McKinlay SM, Vass K. The evolution of menopausal symptoms. Baillieres Clin Endocrinol Metab. 1993;7(1):17–32. https://pubmed.ncbi.nlm.nih.gov/8435051/

4206

Lock M. Contested meanings of the menopause. Lancet. 1991;337(8752):1270–2. https://pubmed.ncbi.nlm.nih.gov/1674073/

4207

Lock M. Ambiguities of aging: Japanese experience and perceptions of menopause. Cult Med Psychiatry. 1986;10(1):23–46. https://pubmed.ncbi.nlm.nih.gov/3486095/

4208

Avis NE, Stellato R, Crawford S, et al. Is there a menopausal syndrome? Menopausal status and symptoms across racial/ethnic groups. Soc Sci Med. 2001;52(3):345–56. https://pubmed.ncbi.nlm.nih.gov/11330770/

4209

Taku K, Melby MK, Kronenberg F, Kurzer MS, Messina M. Extracted or synthesized soybean isoflavones reduce menopausal hot flash frequency and severity: systematic review and meta-analysis of randomized controlled trials. Menopause. 2012;19(7):776–90. https://pubmed.ncbi.nlm.nih.gov/22433977/

4210

Ghazanfarpour M, Sadeghi R, Roudsari RL. The application of soy isoflavones for subjective symptoms and objective signs of vaginal atrophy in menopause: a systematic review of randomised controlled trials. J Obstet Gynaecol. 2016;36(2):160–71. https://pubmed.ncbi.nlm.nih.gov/26440219/

4211

Lambert MNT, Hu LM, Jeppesen PB. A systematic review and meta-analysis of the effects of isoflavone formulations against estrogen-deficient bone resorption in peri– and postmenopausal women. Am J Clin Nutr. 2017;106(3):801–11. https://pubmed.ncbi.nlm.nih.gov/28768649/

4212

Su BYW, Tung TH, Chien WH. Effects of phytoestrogens on depressive symptoms in climacteric women: a meta-analysis of randomized controlled trials. J Altern Complement Med. 2018;24(8):850–1. https://pubmed.ncbi.nlm.nih.gov/29717895/

4213

Cheng PF, Chen JJ, Zhou XY, et al. Do soy isoflavones improve cognitive function in postmenopausal women? A meta-analysis. Menopause. 2015;22(2):198–206. https://pubmed.ncbi.nlm.nih.gov/25003621/

4214

Schmidt M, Arjomand-Wölkart K, Birkhäuser MH, et al. Consensus: soy isoflavones as a first-line approach to the treatment of menopausal vasomotor complaints. Gynecol Endocrinol. 2016;32(6):427–30. https://pubmed.ncbi.nlm.nih.gov/26943176/

4215

Welty FK, Lee KS, Lew NS, Nasca M, Zhou JR. The association between soy nut consumption and decreased menopausal symptoms. J Womens Health (Larchmt). 2007;16(3):361–9. https://pubmed.ncbi.nlm.nih.gov/17439381/

4216

Barnard ND, Kahleova H, Holtz DN, et al. A dietary intervention for vasomotor symptoms of menopause: a randomized, controlled trial. Menopause. 2023;30(1):80–7. https://pubmed.ncbi.nlm.nih.gov/36253903/

4217

Barnard ND, Kahleova H, Holtz DN, et al. The Women’s Study for the Alleviation of Vasomotor Symptoms (WAVS): a randomized, controlled trial of a plant-based diet and whole soybeans for postmenopausal women. Menopause. 2021;28(10):1150–6. https://pubmed.ncbi.nlm.nih.gov/34260478/

4218

Buja A, Pierbon M, Lago L, Grotto G, Baldo V. Breast cancer primary prevention and diet: an umbrella review. Int J Environ Res Public Health. 2020;17(13):E4731. https://pubmed.ncbi.nlm.nih.gov/32630215/

4219

Messina M, Messina VL. Exploring the soyfood controversy. Nutr Today. 2013;48(2):68. https://www.researchgate.net/publication/271683198_Exploring_the_Soyfood_Controversy

4220

Nachvak SM, Moradi S, Anjom-Shoae J, et al. Soy, soy isoflavones, and protein intake in relation to mortality from all causes, cancers, and cardiovascular diseases: a systematic review and dose-response meta-analysis of prospective cohort studies. J Acad Nutr Diet. 2019;119(9):1483–1500.e17. https://pubmed.ncbi.nlm.nih.gov/31278047/

4221

Kelsey JL. A review of the epidemiology of human breast cancer. Epidemiol Rev. 1979;1:74–109. https://pubmed.ncbi.nlm.nih.gov/398270/

4222

Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2021. CA Cancer J Clin. 2021;71(1):7–33. https://pubmed.ncbi.nlm.nih.gov/33433946/

4223

Fraser GE, Jaceldo-Siegl K, Orlich M, Mashchak A, Sirirat R, Knutsen S. Dairy, soy, and risk of breast cancer: those confounded milks. Int J Epidemiol. 2020;49(5):1526–37. https://pubmed.ncbi.nlm.nih.gov/32095830/

4224

Shu XO, Zheng Y, Cai H, et